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1.
European Journal of Psychology Open ; 81(2):47-56, 2022.
Article in English | APA PsycInfo | ID: covidwho-2271558

ABSTRACT

Introduction: The COVID-19 pandemic increased the demand for mental-health services worldwide. Consequently, it also increased the length of the waitlists for mental-health services, putting a strain on adult mental-health services (AMHS) and the healthcare professionals dealing with these lists. There is little research about how psychologists managed waitlist practices, e.g., scheduling screening appointments, determining clients' availability in an offered appointment, providing evidence-based bibliotherapy, or using priority waiting scales. It remains unclear what their experiences were with these practices and how effective these practices were during the pandemic. Method: The current convergent, concurrent mixed-method study investigated waitlist-management practices, synthesizing quantitative and qualitative data from an online survey (n = 20 participants) applied in two local AMHS in Ireland. Results: The most common practices used by psychologists were opt-in systems, maintaining regular contact with clients, informing them about the waiting time, and providing evidence-based bibliotherapy. Screening was the least-used practice. The qualitative analysis highlights the emotional burden psychologists experienced from the use of waitlist practices, particularly when they had to inform the client of the waiting time or put a client back onto a waitlist. Discussion: Psychologists reported a lack of resources and increases in administrative workload as barriers to implementing practices. Managerial, organizational, and policy-based recommendations are proposed. (PsycInfo Database Record (c) 2022 APA, all rights reserved)

2.
Kidney360 ; 3(10): 1754-1762, 2022 10 27.
Article in English | MEDLINE | ID: covidwho-2111637

ABSTRACT

Background: The coronavirus disease 2019 (COVID-19) pandemic created unprecedented challenges for solid organ transplant centers worldwide. We sought to assess an international perspective on COVID-19 vaccine mandates and rationales for or against mandate policies. Methods: We administered an electronic survey to staff at transplant centers outside the United States (October 14, 2021-January 28, 2022) assessing the reasons cited by transplant centers for or against implementing a COVID-19 vaccine mandate. Each responding center was represented once in the analysis. Results: Respondents (N=90) represented 27 countries on five continents. Half (51%) of responding transplant center representatives reported implementing a COVID-19 vaccine mandate, 38% did not, and 12% were unsure. Staff at centers implementing a vaccine mandate cited efficacy of pretransplant vaccination versus post-transplant vaccination, importance for public health, and minimizing exposure of other patients as rationale for the mandate. Of centers with a mandate, the majority (81%) of the centers mandate vaccination regardless of prior SARS-CoV-2 infection status and regardless of prevaccination spike-protein antibody titer or other markers of prior infection. Only 27% of centers with a vaccine mandate for transplant candidates also extended a vaccine requirement to living donor candidates. Centers not implementing a vaccine mandate cited concerns for undue pressure on transplant candidates, insufficient evidence to support vaccine mandates, equity, and legal considerations. Conclusions: The approach to pretransplant COVID-19 vaccination mandate policies at international transplant centers is heterogeneous. International transplant centers with a vaccine mandate were more willing to extend vaccine requirements to candidates' support persons, cohabitants, and living donors. Broader stakeholder engagement to overcome vaccine hesitancy across the world is needed to increase the acceptance of pretransplant COVID-19 vaccination to protect the health of transplant patients.


Subject(s)
COVID-19 , Transplants , Humans , COVID-19 Vaccines/therapeutic use , COVID-19/epidemiology , SARS-CoV-2 , Vaccination
3.
European Journal of Psychology Open ; 2022.
Article in English | Web of Science | ID: covidwho-2016565

ABSTRACT

Introduction: The COVID-19 pandemic increased the demand for mental-health services worldwide. Consequently, it also increased the length of the waitlists for mental-health services, putting a strain on adult mental-health services (AMHS) and the healthcare professionals dealing with these lists. There is little research about how psychologists managed waitlist practices, e.g., scheduling screening appointments, determining clients' availability in an offered appointment, providing evidence-based bibliotherapy, or using priority waiting scales. It remains unclear what their experiences were with these practices and how effective these practices were during the pandemic. Method: The current convergent, concurrent mixed-method study investigated waitlist-management practices, synthesizing quantitative and qualitative data from an online survey (n = 20 participants) applied in two local AMHS in Ireland. Results: The most common practices used by psychologists were opt-in systems, maintaining regular contact with clients, informing them about the waiting time, and providing evidence-based bibliotherapy. Screening was the least-used practice. The qualitative analysis highlights the emotional burden psychologists experienced from the use of waitlist practices, particularly when they had to inform the client of the waiting time or put a client back onto a waitlist. Discussion: Psychologists reported a lack of resources and increases in administrative workload as barriers to implementing practices. Managerial, organizational, and policy-based recommendations are proposed.

4.
Clin Transplant ; 36(4): e14563, 2022 04.
Article in English | MEDLINE | ID: covidwho-1612858

ABSTRACT

INTRODUCTION: Healthcare provision has been severely affected by COVID-19, with specific challenges in organ transplantation. Here, we describe the coordinated response to, and outcomes during the first wave, across all UK liver transplant (LT) centers. METHODS: Several policy changes affecting the liver transplant processes were agreed upon. These included donor age restrictions and changes to offering. A "high-urgency" (HU) category was established, prioritizing only those with UKELD > 60, HCC reaching transplant criteria, and others likely to die within 90 days. Outcomes were compared with the same period in 2018 and 2019. RESULTS: The retrieval rate for deceased donor livers (71% vs. 54%; P < .0001) and conversion from offer to completed transplant (63% vs. 48%; P < .0001) was significantly higher. Pediatric LT activity was maintained; there was a significant reduction in adult (42%) and total (36%) LT. Almost all adult LT were super-urgent (n = 15) or HU (n = 133). We successfully prioritized those with highest illness severity with no reduction in 90-day patient (P = .89) or graft survival (P = .98). There was a small (5% compared with 3%; P = .0015) increase in deaths or removals from the waitlist, mainly amongst HU cohort. CONCLUSIONS: We successfully prioritized LT recipients in highest need, maintaining excellent outcomes, and waitlist mortality was only marginally increased.


Subject(s)
COVID-19 , Carcinoma, Hepatocellular , Liver Neoplasms , Liver Transplantation , Adult , COVID-19/epidemiology , Child , Humans , Pandemics , Transplant Recipients , United Kingdom/epidemiology , Waiting Lists
5.
Transpl Infect Dis ; 24(1): e13763, 2022 Feb.
Article in English | MEDLINE | ID: covidwho-1592049

ABSTRACT

BACKGROUND: The coronavirus disease 2019 (COVID-19) pandemic has created unprecedented challenges for solid organ transplant programs worldwide. The aim of this study is to assess an international perspective on challenges faced by kidney transplant programs. METHODS: We administered an electronic survey instrument from January 3, 2021 to June 8, 2021 to staff at transplant programs outside the United States that comprised of 10 questions addressing the management of kidney transplant candidates with asymptomatic COVID-19 infection or unvaccinated who receive an organ offer. RESULTS: Respondents (n = 62) represented 19 countries in five continents. Overall, 90.3% of respondents encourage vaccination on the waiting list and prior to planned living donor transplant. Twelve percent of respondents reported that they have decided to inactivate unsensitized candidates (calculated panel reactive antibody, cPRA <80%) until they received the two doses of vaccination, and 7% report inactivating candidates who have received their first vaccine dose pending receipt of their second dose. The majority (88.5%) of international respondents declined organs for asymptomatic, nucleic acid testing (NAT)+ patients during admission without documented prior infection. However, 22.9% of international respondents proceeded with kidney transplant in NAT+ patients who were at least 30 days from initial diagnosis with negative chest imaging. CONCLUSIONS: Practitioners in some countries are less willing to accept deceased donor organs for waitlist candidates with incomplete COVID-19 vaccination status and to wait longer before scheduling living donor transplant, compared to United States practices. Access to vaccinations and other resources may contribute to these differences. More research is needed to guide the optimal approach to vaccination before and after transplant.


Subject(s)
COVID-19 , Kidney Transplantation , COVID-19 Vaccines , Humans , Internationality , Kidney Transplantation/adverse effects , SARS-CoV-2 , United States , Vaccination , Waiting Lists
6.
Am J Transplant ; 22(2): 371-380, 2022 02.
Article in English | MEDLINE | ID: covidwho-1488170

ABSTRACT

Transplant centers seeking to increase coronavirus disease 2019 (COVID-19) vaccine coverage may consider requiring vaccination for healthcare workers or for candidates. The authors summarize current data to inform an ethical analysis of the harms, benefits, and individual and societal impact of mandatory vaccination, concluding that vaccine requirements for healthcare workers and transplant candidates are ethically justified by beneficence, net utility, and fiduciary duty to patients and public health. Implementation strategies should mitigate concerns about respect for autonomy and transparency for both groups. We clarify how the same arguments might be applied to related questions of caregiver vaccination, allocation of other healthcare resources, and mandates for non-COVID-19 vaccines. Finally, we call for effort to achieve global equity in vaccination as soon as possible.


Subject(s)
COVID-19 Vaccines , Vaccination , COVID-19 , Ethical Review , Health Personnel , Humans , Patients
7.
Clin Transplant ; 35(11): e14437, 2021 11.
Article in English | MEDLINE | ID: covidwho-1322733

ABSTRACT

The coronavirus disease 2019 (COVID-19) pandemic has created unprecedented challenges for solid organ transplant programs. While transplant activity has largely recovered, appropriate management of deceased donor candidates who are asymptomatic but have positive nucleic acid testing (NAT) for SARS-CoV-2 is unclear, as this result may reflect active infection or prolonged viral shedding. Furthermore, candidates who are unvaccinated or partially vaccinated continue to receive donor offers. In the absence of robust outcomes data, transplant professionals at US adult kidney transplant centers were surveyed (February 13, 2021 to April 29, 2021) to determine community practice (N: 92 centers, capturing 41% of centers and 57% of transplants performed). The majority (97%) of responding centers declined organs for asymptomatic NAT+ patients without documented prior infection. However, 32% of centers proceed with kidney transplant in NAT+ patients who were at least 30 days from initial diagnosis with negative chest imaging. Less than 7% of programs reported inactivating patients who were unvaccinated or partially vaccinated. In conclusion, despite national recommendations to wait for negative testing, many centers are proceeding with kidney transplant in patients with positive SARS-CoV-2 NAT results due to presumed viral shedding. Furthermore, few centers are requiring COVID-19 vaccination prior to transplantation at this time.


Subject(s)
COVID-19 , Adult , Asymptomatic Infections , COVID-19 Vaccines , Humans , SARS-CoV-2 , Vaccination
8.
Am J Transplant ; 21(7): 2563-2572, 2021 07.
Article in English | MEDLINE | ID: covidwho-1146333

ABSTRACT

The COVID-19 pandemic has affected all portions of the global population. However, many factors have been shown to be particularly associated with COVID-19 mortality including demographic characteristics, behavior, comorbidities, and social conditions. Kidney transplant candidates may be particularly vulnerable to COVID-19 as many are dialysis-dependent and have comorbid conditions. We examined factors associated with COVID-19 mortality among kidney transplant candidates from the National Scientific Registry of Transplant Recipients from March 1 to December 1, 2020. We evaluated crude rates and multivariable incident rate ratios (IRR) of COVID-19 mortality. There were 131 659 candidates during the study period with 3534 all-cause deaths and 384 denoted a COVID-19 cause (5.00/1000 person years). Factors associated with increased COVID-19 mortality included increased age, males, higher body mass index, and diabetes. In addition, Blacks (IRR = 1.96, 95% C.I.: 1.43-2.69) and Hispanics (IRR = 3.38, 95% C.I.: 2.46-4.66) had higher COVID-19 mortality relative to Whites. Patients with lower educational attainment, high school or less (IRR = 1.93, 95% C.I.: 1.19-3.12, relative to post-graduate), Medicaid insurance (IRR = 1.73, 95% C.I.: 1.26-2.39, relative to private), residence in most distressed neighborhoods (fifth quintile IRR = 1.93, 95% C.I.: 1.28-2.90, relative to first quintile), and most urban and most rural had higher adjusted rates of COVID-19 mortality. Among kidney transplant candidates in the United States, social determinants of health in addition to demographic and clinical factors are significantly associated with COVID-19 mortality.


Subject(s)
COVID-19 , Kidney Transplantation , Humans , Kidney Transplantation/adverse effects , Male , Pandemics , SARS-CoV-2 , Social Determinants of Health , United States/epidemiology
9.
Am J Transplant ; 21(6): 2262-2268, 2021 06.
Article in English | MEDLINE | ID: covidwho-1096670

ABSTRACT

We examined the effects of COVID-19 on solid organ waiting list mortality in the United States and compared effects across patient demographics (e.g., race, age, and sex) and donation service areas. Three separate piecewise exponential survival models estimated for each solid organ the overall, demographic-specific, and donation service area-specific differences in the hazard of waitlist mortality before and after the national emergency declaration on March 13, 2020. Kidney waiting list mortality was higher after than before the national emergency (adjusted hazard ratio [aHR], 1.37; 95% CI, 1.23-1.52). The hazard of waitlist mortality was not significantly different before and after COVID-19 for liver (aHR, 0.94), pancreas (aHR, 1.01), lung (aHR, 1.00), and heart (aHR, 0.94). Kidney candidates had notable variability in differences across donation service areas (aHRs, New York City, 2.52; New Jersey, 1.84; and Michigan, 1.56). The only demographic group with increased waiting list mortality were Blacks versus Whites (aHR, 1.41; 95% CI, 1.07-1.86) for kidney candidates. The first 10 weeks after the declaration of a national emergency had a heterogeneous effect on waitlist mortality rate, varying by geography and ethnicity. This heterogeneity will complicate comparisons of transplant program performance during COVID-19.


Subject(s)
COVID-19 , Tissue and Organ Procurement , Humans , Michigan , New York City , SARS-CoV-2 , United States/epidemiology , Waiting Lists
10.
Am J Transplant ; 21(6): 2002-2003, 2021 06.
Article in English | MEDLINE | ID: covidwho-991161
11.
Am J Transplant ; 21(5): 1838-1847, 2021 05.
Article in English | MEDLINE | ID: covidwho-892189

ABSTRACT

COVID-19 has profoundly affected the American health care system; its effect on the liver transplant (LT) waitlist based on COVID-19 incidence has not been characterized. Using SRTR data, we compared observed LT waitlist registrations, waitlist mortality, deceased donor LTs (DDLT), and living donor LTs (LDLT) 3/15/2020-8/31/2020 to expected values based on historical trends 1/2016-1/2020, stratified by statewide COVID-19 incidence. Overall, from 3/15 to 4/30, new listings were 11% fewer than expected (IRR = 0.84 0.890.93 ), LDLTs were 49% fewer (IRR = 0.37 0.510.72 ), and DDLTs were 9% fewer (IRR = 0.85 0.910.97 ). In May, new listings were 21% fewer (IRR = 0.74 0.790.84 ), LDLTs were 42% fewer (IRR = 0.39 0.580.85 ) and DDLTs were 13% more (IRR = 1.07 1.151.23 ). Centers in states with the highest incidence 3/15-4/30 had 59% more waitlist deaths (IRR = 1.09 1.592.32 ) and 34% fewer DDLTs (IRR = 0.50 0.660.86 ). By August, waitlist outcomes were occurring at expected rates, except for DDLT (13% more across all incidences). While the early COVID-affected states endured major transplant practice changes, later in the pandemic the newly COVID-affected areas were not impacted to the same extent. These results speak to the adaptability of the transplant community in addressing the pandemic and applying new knowledge to patient care.


Subject(s)
COVID-19 , Liver Transplantation/statistics & numerical data , Humans , Liver Transplantation/trends , Pandemics , Retrospective Studies , United States/epidemiology , Waiting Lists
12.
Am J Transplant ; 21(4): 1586-1596, 2021 04.
Article in English | MEDLINE | ID: covidwho-883239

ABSTRACT

It is unknown if solid organ transplant recipients are at higher risk for severe COVID-19. The management of a lung transplantation (LTx) program and the therapeutic strategies to adapt the immunosuppressive regimen and antiviral measures is a major issue in the COVID-19 era, but little is known about worldwide practice. We sent out to 180 LTx centers worldwide in June 2020 a survey with 63 questions, both regarding the management of a LTx program in the COVID-19 era and the therapeutic strategies to treat COVID-19 LTx recipients. We received a total of 78 responses from 15 countries. Among participants, 81% declared a reduction of the activity and 47% restricted LTx for urgent cases only. Sixteen centers observed deaths on waiting listed patients and eight centers performed LTx for COVID-19 disease. In 62% of the centers, COVID-19 was diagnosed in LTx recipients, most of them not severe cases. The most common immunosuppressive management included a decreased dose or pausing of the cell cycle inhibitors. Remdesivir, hydroxychloroquine, and azithromycin were the most proposed antiviral strategies. Most of the centers have been affected by the COVID-19 pandemic and proposed an active therapeutic strategy to treat LTx recipients with COVID-19.


Subject(s)
COVID-19/diagnosis , Lung Transplantation , Pandemics , COVID-19/therapy , Humans , Immunosuppressive Agents/therapeutic use , Risk Factors , Transplant Recipients , Waiting Lists
13.
Am J Transplant ; 21(4): 1576-1585, 2021 04.
Article in English | MEDLINE | ID: covidwho-843551

ABSTRACT

The COVID-19 pandemic has brought unprecedented challenges to the transplant community. The reduction in transplantation volume during this time is partly due to concerns over potentially increased susceptibility and worsened outcomes of COVID-19 in immunosuppressed recipients. The consequences of COVID-19 on patients waitlisted for kidney transplantation, however, have not previously been characterized. We studied 56 waitlisted patients and 80 kidney transplant recipients diagnosed with COVID-19 between March 13 and May 20, 2020. Despite similar demographics and burden of comorbidities between waitlisted and transplant patients, waitlisted patients were more likely to require hospitalization (82% vs. 65%, P = .03) and were at a higher risk of mortality (34% vs. 16%, P = .02). Intubation was required in one third of hospitalized patients in each group, and portended a very poor prognosis. The vast majority of patients who died were male (84% waitlist, 100% transplant). Multivariate analysis demonstrated waitlist status, age, and male sex were independently associated with mortality. COVID-19 has had a dramatic impact on waitlisted patients, decreasing their opportunities for transplantation and posing significant mortality risk. Understanding the impact of COVID-19 on waitlist patients in comparison to transplant recipients may aid centers in weighing the risks and benefits of transplantation in the setting of ongoing COVID-19.


Subject(s)
COVID-19/complications , Kidney Transplantation , Transplant Recipients , Waiting Lists , Adult , Aged , Aged, 80 and over , COVID-19/mortality , Female , Hospitalization , Humans , Male , Middle Aged , Pandemics
14.
15.
Am J Transplant ; 20(11): 3113-3122, 2020 11.
Article in English | MEDLINE | ID: covidwho-592283

ABSTRACT

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), a novel coronavirus responsible for a worldwide pandemic has forced drastic changes in medical practice in an alarmingly short period of time. Caregivers must modify their strategies as well as optimize the utilization of resources to ensure public and patient safety. For organ transplantation, in particular, the loss of lifesaving organs for transplantation could lead to increased waitlist mortality. The priority is to select uninfected donors to transplant uninfected recipients while maintaining safety for health care systems in the backdrop of a virulent pandemic. We do not yet have a standard approach to evaluating donors and recipients with possible SARS-CoV-2 infection. Our current communication shares a protocol for donor and transplant recipient selection during the coronavirus disease 2019 (COVID-19) pandemic to continue lifesaving solid organ transplantation for heart, lung, liver, and kidney recipients. The initial results using this protocol are presented here and meant to encourage dialogue between providers, offering ideas to improve safety in solid organ transplantation with limited health care resources. This protocol was created utilizing the guidelines of various organizations and from the clinical experience of the authors and will continue to evolve as more is understood about SARS-CoV-2 and how it affects organ donors and transplant recipients.


Subject(s)
COVID-19/epidemiology , Organ Transplantation/methods , Pandemics , Patient Selection , Tissue Donors , Tissue and Organ Procurement/organization & administration , Transplant Recipients/statistics & numerical data , Humans , SARS-CoV-2 , Waiting Lists
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